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25 mai 2009

The Smoking Vaccine

Scientists create a miracle cure – a shot of medicine to take away the kick that keeps people hooked on nicotine. Two companies are developing a vaccine that will neutralize nicotine’s hold on the brain by keeping it from getting there first of all. If either of them has success, millions of smokers could trash their soft packs for good, reducing their risk of dozens of ailments, including heart stroke, disease and 10 different types of cancer. Vaccine is designed to stimulate antibodies in the bloodstream that identify and bond with nicotine and protect it from entering the brain.

Henrik Rasmussen, M.D., Ph.D., of Nabi says: “It’s based on the assumption that the main reason smokers can’t quit is that they miss the rush they get when the nicotine hits the brain. We are basically attempting to block that, so you lose the feeling of well-being that cigarettes give you.” The vaccine is going to be a revolutionary approach to tobacco-addiction treatment.

 

The NicVax vaccine offers a lot more protection than other treatment methods. Eight shots over a 12-month period will cover patients for the year. With NicVax, a smoker is stuck and that is what he needs. Researches have shown that if a smoker makes it past a year without relapse, his chances of staying smoke-free are very good.

 

The government puts its money on NicVax – the National Institute on Drug Abuse (NIDA) has given a healthy dose of funding to carry out clinical trials at the

University

of

Wisconsin

, the

University

of

Minnesota

and the

University

of

Nebraska

. Francis Rocci, Ph.D., a researcher on nicotine addiction at the NIDA says: “This is a new paradigm, and it’s working on the concept of drug priming. If someone had a relapse and picked up a cigarette, he wouldn’t get the priming effect of smoking. The vaccine blocks the nicotine spike that can take you from two cigarettes at a party Friday night to running down to the 7-Eleven and buying a pack on Saturday morning.” Rocci adds: “This could be therapeutic, somewhat like a patch. It releases the nicotine into the blood at a very slow rate, so you won’t get a buzz, but it will probably keep smokers from going into withdrawal.”

05 mai 2009

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